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6 Approximately 70% of patients who enter phase four recover completely, while 1% to 2% of patients develop fatal hepatic failure

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If the acetaminophen concentration cannot be obtained (or is unavailable or uninterpretable) within the 8- hour time interval after acetaminophen ingestion or there is clinical evidence of acetaminophen toxicity: Administer a loading dose of ACETADOTE immediately and continue treatment for a total of three doses over 21 hours